USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P56537 USC-OGP 2-DE database:  P56537 P56537 General information about the entry View entry in simple text format Entry name IF6_HUMAN Primary accession number P56537 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Eukaryotic translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_03132}; Short=eIF-6 {ECO:0000255|HAMAP-Rule:MF_03132}; AltName: Full=B(2)GCN homolog; AltName: Full=B4 integrin interactor; AltName: Full=CAB; AltName: Full=p27(BBP);. Gene name Name=EIF6 {ECO:0000255|HAMAP-Rule:MF_03132, ECO:0000312|HGNC:HGNC:6159} Synonyms=EIF3A, ITGB4BP {ECO:0000255|HAMAP-Rule:MF_03132} ORFNames=OK/SW-cl.27 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0177: pI=4.56; Mw=27032 Cross-references UniProtKB/Swiss-Prot P56537; IF6_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name IF6_HUMAN Primary accession number P56537 Secondary accession number(s) B7ZBG9 Q6IBN8 Q96TD5 Sequence was last modified on  July 15, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 170) Name and origin of the protein Description RecName: Full=Eukaryotic translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_03132}; Short=eIF-6 {ECO:0000255|HAMAP-Rule:MF_03132}; AltName: Full=B(2)GCN homolog; AltName: Full=B4 integrin interactor; AltName: Full=CAB; AltName: Full=p27(BBP); Gene name Name=EIF6 {ECO:0000255|HAMAP-Rule:MF_03132, ECO:0000312|HGNC:HGNC:6159} Synonyms=EIF3A, ITGB4BP {ECO:0000255|HAMAP-Rule:MF_03132} ORFNames=OK/SW-cl.27 Encoded on Name=EIF6 {ECO:0000255|HAMAP-Rule:MF_03132, ECO:0000312|HGNC:HGNC:6159}; Synonyms=EIF3A, ITGB4BP {ECO:0000255|HAMAP-Rule:MF_03132}; ORFNames=OK/SW-cl.27 Keywords Alternative splicing; Complete proteome; Cytoplasm; Initiation factor; Nucleus; Phosphoprotein; Protein biosynthesis; Reference proteome; Ribosome biogenesis. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF022229; AAB97735.1; -; mRNA EMBL Y11435; CAA72243.1; -; mRNA EMBL AF289541; AAK39426.1; -; Genomic_DNA EMBL AF289540; AAK39426.1; JOINED; Genomic_DNA EMBL AF047433; AAC39897.1; -; mRNA EMBL AK314969; BAG37470.1; -; mRNA EMBL AB062289; BAB93472.1; -; mRNA EMBL CR456764; CAG33045.1; -; mRNA EMBL AL121753; CAX12724.1; -; Genomic_DNA EMBL CH471077; EAW76221.1; -; Genomic_DNA EMBL BC001119; AAH01119.1; -; mRNA EMBL BC011845; AAH11845.1; -; mRNA EMBL BC019305; AAH19305.1; -; mRNA CCDS CCDS13249.1; -. [P56537-1]; . CCDS CCDS13250.1; -. [P56537-2]; . RefSeq NP_001254739.1; NM_001267810.1. [P56537-1]; . RefSeq NP_002203.1; NM_002212.3. [P56537-1]; . RefSeq NP_852131.1; NM_181466.2. [P56537-2]; . RefSeq NP_852133.1; NM_181468.2. [P56537-1]; . UniGene Hs.743992; -; . ProteinModelPortal P56537; -; . SMR P56537; -; . BioGrid 109898; 143; . IntAct P56537; 24; . MINT MINT-2804329; -; . STRING 9606.ENSP00000363559; -; . Allergome 8361; Hom s eIF6; . iPTMnet P56537; -; . PhosphoSitePlus P56537; -; . SwissPalm P56537; -; . BioMuta EIF6; -; . OGP P56537; -; . REPRODUCTION-2DPAGE IPI00010105; -; . SWISS-2DPAGE P56537; -; . EPD P56537; -; . MaxQB P56537; -; . PaxDb P56537; -; . PeptideAtlas P56537; -; . PRIDE P56537; -; . TopDownProteomics P56537-1; -. [P56537-1]; . DNASU 3692; -; . Ensembl ENST00000374436; ENSP00000363559; ENSG00000242372. [P56537-1]; . Ensembl ENST00000374443; ENSP00000363566; ENSG00000242372. [P56537-2]; . Ensembl ENST00000374450; ENSP00000363574; ENSG00000242372. [P56537-1]; . Ensembl ENST00000621148; ENSP00000483289; ENSG00000242372. [P56537-1]; . GeneID 3692; -; . KEGG hsa:3692; -; . UCSC uc002xbv.3; human. [P56537-1]; . CTD 3692; -; . DisGeNET 3692; -; . GeneCards EIF6; -; . HGNC HGNC:6159; EIF6; . HPA HPA040873; -; . MIM 602912; gene; . neXtProt NX_P56537; -; . OpenTargets ENSG00000242372; -; . PharmGKB PA29958; -; . eggNOG KOG3185; Eukaryota; . eggNOG COG1976; LUCA; . GeneTree ENSGT00390000015972; -; . HOGENOM HOG000230605; -; . HOVERGEN HBG001300; -; . InParanoid P56537; -; . KO K03264; -; . OMA NDWCAFT; -; . OrthoDB EOG091G0HYF; -; . PhylomeDB P56537; -; . TreeFam TF105396; -; . SIGNOR P56537; -; . ChiTaRS EIF6; human; . GeneWiki EIF6; -; . GenomeRNAi 3692; -; . PRO PR:P56537; -; . Proteomes UP000005640; Chromosome 20; . Bgee ENSG00000242372; -; . CleanEx HS_EIF3A; -; . CleanEx HS_EIF6; -; . ExpressionAtlas P56537; baseline and differential; . Genevisible P56537; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IBA:GO_Central; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005730; C:nucleolus; IBA:GO_Central; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0030687; C:preribosome; large subunit precursor; IBA:GO_Central GO GO:0043023; F:ribosomal large subunit binding; IBA:GO_Central; . GO GO:0043022; F:ribosome binding; IDA:UniProtKB; . GO GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW; . GO GO:1902626; P:assembly of large subunit precursor of preribosome; IBA:GO_Central; . GO GO:0035195; P:gene silencing by miRNA; IMP:UniProtKB; . GO GO:0000460; P:maturation of 5.8S rRNA; IBA:GO_Central; . GO GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central; . GO GO:0042256; P:mature ribosome assembly; IMP:UniProtKB; . GO GO:0035278; P:miRNA mediated inhibition of translation; IMP:UniProtKB; . GO GO:0045727; P:positive regulation of translation; ISS:UniProtKB; . GO GO:0042304; P:regulation of fatty acid biosynthetic process; ISS:UniProtKB; . GO GO:0006110; P:regulation of glycolytic process; ISS:UniProtKB; . GO GO:0045652; P:regulation of megakaryocyte differentiation; ISS:UniProtKB; . GO GO:2000377; P:regulation of reactive oxygen species metabolic process; ISS:UniProtKB; . GO GO:0032868; P:response to insulin; ISS:UniProtKB; . GO GO:0000054; P:ribosomal subunit export from nucleus; IBA:GO_Central; . CDD cd00527; IF6; 1; . HAMAP MF_00032; eIF_6; 1; . InterPro IPR002769; eIF6; . PANTHER PTHR10784; PTHR10784; 1; . Pfam PF01912; eIF-6; 1; . PIRSF PIRSF006413; IF-6; 1; . SMART SM00654; eIF6; 1; . TIGRFAMs TIGR00323; eIF-6; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]